Alton is a city on the Mississippi River in Madison County, Illinois, United States, about 18 miles (29 km) north of St. Louis, Missouri. The population was 25,676 at the 2020 census. It is a part of the River Bend area in the Metro-East region of the Greater St. Louis metropolitan area. It is famous for its limestone bluffs along the river north of the city, as the former location of the state penitentiary, and for its role preceding and during the American Civil War. It was the site of the last Abraham Lincoln and Stephen Douglas debate in October 1858. The former state penitentiary in Alton was used during the Civil War to hold up to 12,000 Confederate prisoners of war. Also, the tallest man in history, Robert Wadlow, was born and raised in Alton.

Madison County is a county in the U.S. state of Illinois. It is a part of the Metro East in southern Illinois. According to the 2020 census, it had a population of 264,776, making it the eighth-most populous county in Illinois and the most populous in the southern portion of the state. The county seat is Edwardsville, and the largest city is Granite City.