American Eagle is a brand name for the regional branch of American Airlines, under which six individual regional airlines operate short- and medium-haul feeder flights. Three of these airlines, Envoy Air, Piedmont Airlines, and PSA Airlines, are wholly owned subsidiaries of the American Airlines Group. American Eagle's largest hub is Charlotte Douglas International's Concourse E, which operates over 340 flights per day, making it the largest express flight operation in the world.

American Airlines is a major airline in the United States headquartered in Fort Worth, Texas, within the Dallas–Fort Worth metroplex. It is the largest airline in the world when measured by scheduled passengers carried, revenue passenger mile. American, together with its regional partners and affiliates, operates an extensive international and domestic network with almost 6,800 flights per day to nearly 350 destinations in 48 countries. American Airlines is a founding member of the Oneworld alliance. Regional service is operated by independent and subsidiary carriers under the brand name American Eagle.