Amr ibn al-As ibn Wa'il al-Sahmi was the Arab commander who led the Muslim conquest of Egypt and served as its governor in 640–646 and 658–664. The son of a wealthy Qurayshite, Amr embraced Islam in c. 629 and was assigned important roles in the nascent Muslim community by the Islamic prophet Muhammad. The first caliph Abu Bakr appointed Amr as a commander of the conquest of Syria. He conquered most of Palestine, to which he was appointed governor, and helped lead the Arabs to decisive victories over the Byzantines at the battles of Ajnadayn and the Yarmuk in 634 and 636.

The Arab conquest of Egypt, led by the army of 'Amr ibn al-'As, took place between 639 and 642 AD and was overseen by the Rashidun Caliphate. It ended the seven-century-long Roman period in Egypt that began in 30 BC, and widely speaking Greco-Roman period that had lasted about a millennium.