Anglesey is an island off the north-west coast of Wales. It forms the bulk of the county known as the Isle of Anglesey, which also includes Holy Island and some islets and skerries. The county borders Gwynedd across the Menai Strait to the southeast, and is otherwise surrounded by the Irish Sea. Holyhead is the largest town, and the administrative centre is Llangefni. The county is part of the preserved county of Gwynedd.

The Irish Sea is a 46,007 km2 (17,763 sq mi) body of water that separates the islands of Ireland and Great Britain. It is linked to the Celtic Sea in the south by St George's Channel and to the Inner Seas off the West Coast of Scotland in the north by the North Channel. Anglesey, North Wales, is the largest island in the Irish Sea, followed by the Isle of Man. The term Manx Sea may occasionally be encountered.