Assyriology, also known as Cuneiform studies or Ancient Near East studies, is the archaeological, anthropological, historical, and linguistic study of the cultures that used cuneiform writing. The field covers Pre Dynastic Mesopotamia, Sumer, the early Sumero-Akkadian city-states, the Akkadian Empire, Ebla, the Akkadian and Imperial Aramaic speaking states of Assyria, Babylonia and the Sealand Dynasty, the migrant foreign dynasties of southern Mesopotamia, including the Gutians, Amorites, Kassites, Arameans, Suteans and Chaldeans. Assyriology can be included to cover Neolithic pre-Dynastic cultures dating to as far back as 8000 BC, to the Islamic Conquest of the 7th century AD, so the topic is significantly wider than that implied by the root "Assyria".

Cuneiform is a logo-syllabic writing system that was used to write several languages of the Ancient Near East. The script was in active use from the early Bronze Age until the beginning of the Common Era. Cuneiform scripts are marked by and named for the characteristic wedge-shaped impressions which form their signs. Cuneiform is the earliest known writing system and was originally developed to write the Sumerian language of southern Mesopotamia.