Athens is a city and the county seat of Athens County, Ohio, United States. The population was 23,849 at the 2020 census. Located along the Hocking River within Appalachian Ohio about 65 miles (105 km) southeast of Columbus, Athens is best known as the home of Ohio University, a large public research university with an undergraduate and graduate enrollment of more than 21,000 students. It is the principal city of the Athens micropolitan area.

Athens County is a county in southeastern Ohio. As of the 2020 census, the population was 62,431. Its county seat and largest city is Athens. The county was formed in 1805 from Washington County. Because Ohio's first state university, Ohio University, was established here in 1804, the town and the county are named for the ancient center of learning, Athens, Greece.