The Battle of San Domingo was a naval battle of the Napoleonic Wars fought on 6 February 1806 between squadrons of French and British ships of the line off the southern coast of the French-occupied Spanish colonial Captaincy General of Santo Domingo in the Caribbean.

Admiral Sir John Thomas Duckworth, 1st Baronet, GCB was an English officer of the Royal Navy, serving during the Seven Years' War, the American War of Independence, the French Revolutionary and Napoleonic wars, as the Governor of Newfoundland during the War of 1812, and a member of the British House of Commons during his semi-retirement. Duckworth, a vicar's son, achieved much in a naval career that began at the age of 11.