Belgium participated at the Eurovision Song Contest 2010 with the song "Me and My Guitar" written by Tom Dice, Jeroen Swinnen and Ashley Hicklin. The song was performed by Tom Dice, who was internally selected by the Flemish broadcaster Vlaamse Radio- en Televisieomroeporganisatie (VRT) in November 2009 to represent the nation at the 2010 contest in Oslo, Norway. The song, "Me and My Guitar", was presented to the public on 7 March 2010 during the television special Eurosong 2010: een song voor Tom Dice!.

The Eurovision Song Contest 2010 was the 55th edition of the Eurovision Song Contest. It took place in Oslo, Norway, following the country's victory at the 2009 contest with the song "Fairytale" by Alexander Rybak. Organised by the European Broadcasting Union (EBU) and host broadcaster Norsk rikskringkasting (NRK), the contest was held at the Telenor Arena, and consisted of two semi-finals on 25 and 27 May, and a final on 29 May 2010, tying with the 1999 edition for the contest hosted the latest. The three live shows were presented by Norwegian television presenters Erik Solbakken and Nadia Hasnaoui and singer Haddy N'jie.