The blockade of Saint-Domingue was a naval campaign fought during the first months of the Napoleonic Wars in which a series of British Royal Navy squadrons blockaded the French-held ports of Cap-Français and Môle-Saint-Nicolas on the northern coast of the French colony of Saint-Domingue, soon to become Haiti, after the conclusion of the Haitian Revolution on 1 January 1804. In the summer of 1803, when war broke out between the United Kingdom and the French Consulate, Saint-Domingue had been almost completely overrun by Haitian Armée Indigène troops led by Jean-Jacques Dessalines. In the north of the country, the French forces were isolated in the two large ports of Cap-Français and Môle-Saint-Nicolas and a few smaller settlements, all supplied by a French naval force based primarily at Cap-Français.

The Indigenous Army, also known as the Army of Saint-Domingue was the name bestowed to the coalition of anti-slavery men and women who fought in the Haitian Revolution in Saint-Domingue. Encompassing both black slaves, maroons, and affranchis, the rebels were not officially titled the Armée indigène until January 1803, under the leadership of then-general Jean-Jacques Dessalines. Predated by insurrectionists such as François Mackandal, Vincent Ogé and Dutty Boukman, Toussaint Louverture, succeeded by Dessalines, led, organized, and consolidated the rebellion. The now full-fledged fighting force utilized its manpower advantage and strategic capacity to overwhelm French troops, ensuring the Haitian Revolution was the most successful of its kind.