Buffalo Central Terminal is a historic former railroad station in Buffalo, New York. An active station from 1929 to 1979, the 17-story Art Deco style station was designed by architects Fellheimer & Wagner for the New York Central Railroad. The Central Terminal is located in the city of Buffalo's Broadway/Fillmore district. Closed since 1979, several attempts to redevelop the site were unsuccessful. In February 2024 a new development team was formed to plan a reuse for the terminal.

Buffalo is a city in the U.S. state of New York and the seat of Erie County. It lies in Western New York, at the eastern end of Lake Erie, at the head of the Niagara River, on the United States border with Canada. With a population of 278,349 according to the 2020 census, Buffalo is the 2nd largest city in New York state, 1st being New York City, and the 78th largest city in the United States. Buffalo and the city of Niagara Falls together make up the two-county Buffalo–Niagara Falls Metropolitan Statistical Area (MSA), which had an estimated population of 1.2 million in 2020, making it the 49th-largest MSA in the United States.