The Cadillac DTS is a full-size car that was built by the American company Cadillac from 2005 until May 2011. It is a four-door sedan that comes in five- or six-seat variants. The DTS debuted at the 2005 Chicago Auto Show and was manufactured at GM's Detroit/Hamtramck Assembly factory. It uses GM's G-platform for front-engine, front-wheel-drive automobiles. The DTS was a very mildly revised iteration of the eighth-generation Deville, using the brand's new naming convention, set by the CTS and STS. Writing for the Los Angeles Times, noted reviewer Warren Brown called the DTS "a large, exceptionally comfortable front-wheel-drive luxury sedan." The nameplate DTS is an acronym for DeVille Touring Sedan.

Cadillac Motor Car Division, or simply Cadillac, is a division of the American automobile manufacturer General Motors (GM) that designs and builds luxury vehicles. Its major markets are the United States, Canada and China. Cadillac models are distributed in 34 additional markets worldwide. Historically, Cadillac automobiles were at the top of the luxury field within the United States, but have been outsold by European luxury brands including BMW and Mercedes since the 2000s. In 2019, Cadillac sold 390,458 vehicles worldwide, a record for the brand.