Calhoun County is a county located in the south central part of the U.S. state of Arkansas. As of the 2020 census, the population was 4,739, making it the least populous county in Arkansas. The county seat is Hampton. Calhoun County is Arkansas's 55th county, formed on December 6, 1850, and named for John C. Calhoun, a Vice President of the United States.

Camden is a city in and the county seat of Ouachita County in the south-central part of the U.S. state of Arkansas. The city is located about 100 miles south of Little Rock. Situated on bluffs overlooking the Ouachita River, the city developed because of the river.