Cayenne is the prefecture of French Guiana, an overseas region and department of France located in South America. The city stands on a former island at the mouth of the Cayenne River on the Atlantic coast. The city's motto is "fert aurum industria", which means "work brings wealth". Cayenne is the largest Francophone city of the South American continent.

French Guiana is an overseas department and region of France located on the northern coast of South America in the Guianas and the West Indies. Bordered by Suriname to the west and Brazil to the east and south, French Guiana covers a total area of 84,000 km2 (32,000 sq mi) and a land area of 83,534 km2 (32,253 sq mi), and is inhabited by 295,385 people.