Chemical element
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A chemical element is a chemical substance that cannot be broken down into other substances by chemical reactions. The basic particle that constitutes a chemical element is the atom. Chemical elements are identified by the number of protons in the nuclei of their atoms, known as the element's atomic number. For example, oxygen has an atomic number of 8, meaning that each oxygen atom has 8 protons in its nucleus. Two or more atoms of the same element can combine to form molecules, in contrast to chemical compounds or mixtures, which contain atoms of different elements. Atoms can be transformed into different elements in nuclear reactions, which change an atom's atomic number.
Estimated distribution of dark matter and dark energy in the universe. Only the fraction of the mass and energy in the universe labeled "atoms" is composed of chemical elements.
Portrait of Robert Boyle, c. 1740
Title page of The Sceptical Chymist, published in 1661
Portrait of Isaac Watts by John Shury, c. 1830
Chemical substance
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A chemical substance is a unique form of matter with constant chemical composition and characteristic properties. Chemical substances may take the form of a single element or chemical compounds. If two or more chemical substances can be combined without reacting, they may form a chemical mixture. If a mixture is separated to isolate one chemical substance to a desired degree, the resulting substance is said to be chemically pure.
Steam and liquid water are two different forms of the same pure chemical substance, water.
Colors of a single chemical (Nile red) in different solvents, under visible and UV light, showing how the chemical interacts dynamically with its solvent environment.
Native sulfur crystals. Sulfur occurs naturally as elemental sulfur, in sulfide and sulfate minerals and in hydrogen sulfide.
Potassium ferricyanide is a compound of potassium, iron, carbon and nitrogen; although it contains cyanide anions, it does not release them and is nontoxic.