The Chinatown centered on Grant Avenue and Stockton Street in San Francisco, California, is the oldest Chinatown in North America and one of the largest Chinese enclaves outside Asia. It is also the oldest and largest of the four notable Chinese enclaves within San Francisco. Since its establishment in the early 1850s, it has been important and influential in the history and culture of ethnic Chinese immigrants in North America. Chinatown is an enclave that has retained its own customs, languages, places of worship, social clubs, and identity.

Stockton Street is a north-south street in San Francisco. It begins at Market Street passing Union Square, a major shopping district in the city. It then runs underground for about two and a half blocks in the Stockton Street Tunnel, passes through Chinatown and North Beach, and ends at Beach Street near the Pier 39 shopping center and tourist attraction.