Colombia competed at the 2012 Summer Olympics in London, from 27 July to 12 August 2012. This was the nation's eighteenth appearance at the Olympics, having not competed at the 1952 Summer Olympics in Helsinki.

At the 2012 Summer Olympics Parade of Nations of the 2012 London Olympics, athletes and officials from each participating country paraded into the Olympic Stadium preceded by their national flag to the sound of iconic British modern music. Each flag bearer was chosen by each nation's National Olympic Committee or by the delegation of athletes.