Concordia Seminary is a Lutheran seminary in Clayton, Missouri. The institution's primary mission is to train pastors, deaconesses, missionaries, chaplains, and church leaders for the Lutheran Church–Missouri Synod (LCMS). Founded in 1839, the seminary initially resided in Perry County, Missouri. In 1849, it was moved to St. Louis, and in 1926, the current campus was built.

The Lutheran Church – Missouri Synod (LCMS), also known as the Missouri Synod, is an orthodox, traditional, confessional Lutheran denomination in the United States. With 1.8 million members as of 2021, it is the second-largest Lutheran body in the United States, behind the Evangelical Lutheran Church in America. The LCMS was organized in 1847 at a meeting in Chicago, Illinois, as the German Evangelical Lutheran Synod of Missouri, Ohio, and Other States, a name which partially reflected the geographic locations of the founding congregations.