Daphne Crane is a fictional character on the American television sitcom Frasier, played by Jane Leeves. An English immigrant from Manchester, Daphne is employed by Frasier as a live-in housekeeper and physical therapist for his father, Martin. Her relationship with Frasier's brother Niles is a major plotline of the series, progressing from Niles' secret infatuation to their eventual marriage later on the show.

Jane Elizabeth Leeves is an English actress, best known for her role as Daphne Moon on the NBC sitcom Frasier (1993–2004), for which she was nominated for an Emmy Award and a Golden Globe Award. She also played Joy Scroggs on TV Land's sitcom Hot in Cleveland.