Downtown is the central business district of Washington, D.C., located in Northwest D.C. It is the third largest central business district in the United States. The "Traditional Downtown" has been defined as an area roughly between Union Station in the east and 16th Street NW in the west, and between the National Mall on the south and Massachusetts Avenue on the north, including Penn Quarter. However, nowadays, Downtown D.C. usually refers to a larger area, as the DC Office of Planning states:…most residents, workers, and visitors think of Downtown in a broader sense — including areas as far north as Dupont Circle, as far west as Foggy Bottom, and as far east as Capitol Hill. Only about half of the central city workforce is located within the city’s traditional Downtown.

Northwest is the northwestern quadrant of Washington, D.C., the capital of the United States, and is located north of the National Mall and west of North Capitol Street. It is the largest of the four quadrants of the city, and it includes the central business district, the Federal Triangle, and the museums along the northern side of the National Mall, as well as many of the District's historic neighborhoods.