The Dutch–Portuguese War was a global armed conflict involving Dutch forces, in the form of the Dutch East India Company, the Dutch West India Company, and their allies, against the Iberian Union, and after 1640, the Portuguese Empire. Beginning in 1598, the conflict primarily involved the Dutch companies and fleet invading Portuguese colonies in the Americas, Africa, and the East Indies. The war can be thought of as an extension of the Eighty Years' War being fought in Europe at the time between Spain and the Netherlands, as Portugal was in a dynastic union with Spain after the War of the Portuguese Succession, for most of the conflict.

The United East India Company, commonly known as the Dutch East India Company, was a chartered trading company and one of the first joint-stock companies in the world. Established on 20 March 1602 by the States General of the Netherlands amalgamating existing companies, it was granted a 21-year monopoly to carry out trade activities in Asia. Shares in the company could be purchased by any citizen of the United Provinces and then subsequently bought and sold in open-air secondary markets. The company possessed quasi-governmental powers, including the ability to wage war, imprison and execute convicts, negotiate treaties, strike its own coins, and establish colonies. Also, because it traded across multiple colonies and countries from both the East and the West, the VOC is sometimes considered to have been the world's first multinational corporation.