Fort Santo Domingo is a historical fortress in Tamsui District, New Taipei City, Taiwan. It was originally a wooden fort built in 1628 by the Spanish Empire, who named it "Fort Santo Domingo". However, the fort was then destroyed by the Spanish themselves, after losing the Second Battle of San Salvador to the Dutch Empire in 1642. After the battle, in 1644, the Dutch rebuilt a fort in the original site and renamed it "Fort Antonio". Since the Dutch were called "Red-haired People" by the Han immigrants during the time, the fort was then nicknamed "Fort Red Hair".(Chinese: 紅毛城; Pe̍h-ōe-jī: Âng-mn̂g-siâⁿ; lit. 'ang mo fort').

Tamsui District is a seaside district in New Taipei City, Taiwan adjacent to the Tamsui River and overlooking the Taiwan Strait. The name of the district means "fresh water" in Chinese. Although modest in size, Tamsui plays a significant role in Taiwanese history and culture.