Gemini 8 was the sixth crewed spaceflight in NASA's Gemini program. It was launched on March 16, 1966, and was the 14th crewed American flight and the 22nd crewed spaceflight overall. The mission conducted the first docking of two spacecraft in orbit, but also suffered the first critical in-space system failure of a U.S. spacecraft which threatened the lives of the astronauts and required an immediate abort of the mission. The crew returned to Earth safely.

Project Gemini was the second United States human spaceflight program to fly. Conducted after the first American manned space program, Project Mercury, while the Apollo program was still in early development, Gemini was conceived in 1961 and concluded in 1966. The Gemini spacecraft carried a two-astronaut crew. Ten Gemini crews and 16 individual astronauts flew low Earth orbit (LEO) missions during 1965 and 1966.