Greifswald, officially the University and Hanseatic City of Greifswald is the fourth-largest city in the German state of Mecklenburg-Western Pomerania after Rostock, Schwerin and Neubrandenburg. In 2021 it surpassed Stralsund for the first time, and became the largest city in the Pomeranian part of the state. It sits on the River Ryck, at its mouth into the Danish Wiek, a sub-bay of the Bay of Greifswald, which is itself a sub-bay of the Bay of Pomerania of the Baltic Sea.

Mecklenburg-Vorpommern ; also known by its anglicized name Mecklenburg–Western Pomerania, is a state in the north-east of Germany. Of the country's sixteen states, Mecklenburg-Vorpommern ranks 14th in population; it covers an area of 23,300 km2 (9,000 sq mi), making it the sixth largest German state in area; and it is 16th in population density. Schwerin is the state capital and Rostock is the largest city. Other major cities include Neubrandenburg, Stralsund, Greifswald, Wismar, and Güstrow. It was named after the two regions of Mecklenburg and Vorpommern, and its name means the "nearer part of Pomerania", with the rest now lying in Poland.