The Harpeth River, 115 miles (185 km) long, is one of the major streams of north-central Middle Tennessee, United States, and one of the major tributaries of the Cumberland River. Via the Cumberland and the Ohio Rivers, it is part of the Mississippi River watershed. The lower portion of the Harpeth is designated as a "scenic river" under the Tennessee Scenic Rivers Act.

Williamson County is a county in the U.S. state of Tennessee. As of the 2020 United States census, the population was 247,726. The county seat is Franklin, and the county is located in Middle Tennessee. The county is named after Hugh Williamson, a North Carolina politician who signed the U.S. Constitution. Williamson County is part of the Nashville-Davidson–Murfreesboro–Franklin, TN Metropolitan Statistical Area. In the 19th century, tobacco and hemp were cultivated here, and planters also raised blooded livestock, including horses and cattle.