Highlandtown is a neighborhood of Baltimore, Maryland, United States.

Maryland Route 150 (MD 150) is a state highway in the U.S. state of Maryland. Known for most of its length as either Eastern Avenue or Eastern Boulevard, the highway runs 13.01 miles (20.94 km) from U.S. Route 40 (US 40) in Baltimore east to Graces Quarters Road in Chase in eastern Baltimore County. MD 150 connects Baltimore with its southeastern suburbs of Dundalk, Essex, and Middle River. The state highway also links those communities with Interstate 95 (I-95), I-695, I-895, and Martin State Airport. MD 150 was constructed from Baltimore to Middle River and in Chase in the mid-1920s. The road was completed through Middle River in the early 1930s. Between 1942 and 1944, MD 150 was reconstructed as a four-lane divided highway with interchanges to improve access between Baltimore and the Glenn L. Martin Company aircraft manufacturing plant in Middle River. The highway has followed several routes since it was extended west into the city of Baltimore in the mid-1940s; the present route in East Baltimore was established shortly after 2000.