Highway 1 is the main highway in Israel, connecting Tel Aviv and Jerusalem, and continuing eastwards to the Jordan Valley in the West Bank.

Highway 20, more commonly known as the Ayalon Highway, or simply Ayalon, is a major inter city freeway in Gush Dan, Israel. The road runs along the eastern border of central Tel Aviv from north to south and connects all of the major highways leading to the city—such as Highway 4 from Ashdod and the Southern regions, Highway 2 from Haifa and the Northern regions, Highway 5 from the East, and Highway 1 from Jerusalem and the Southeast. The Ayalon Highway is heavily used; on an average day, almost 600,000 vehicles enter the freeway. It consists of a multi-lane highway with a multi-track railway located between the opposite travel lanes. Some of the highway's route is along the Ayalon River, hence its name. It is made of primarily asphalt.