Hiram Edson (1806–1882) was a pioneer of the Seventh-day Adventist Church, known for introducing the sanctuary doctrine to the church. Hiram Edson was a Millerite adventist, and became a Sabbath-keeping Adventist. Like all Millerites, Edson expected that the Second Coming of Jesus Christ would occur on October 22, 1844. This belief was based on an interpretation of the 2300 day prophecy which predicted that "the sanctuary would be cleansed" which Millerites took to mean that Christ would return on that day.

The Seventh-day Adventist Church (SDA) is an Adventist Protestant Christian denomination which is distinguished by its observance of Saturday, the seventh day of the week in the Christian (Gregorian) and the Hebrew calendar, as the Sabbath, its emphasis on the imminent Second Coming (advent) of Jesus Christ, and its annihilationist soteriology. The denomination grew out of the Millerite movement in the United States during the mid-19th century and it was formally established in 1863. Among its co-founders was Ellen G. White, whose extensive writings are still held in high regard by the church.