The House of Hohenlohe is a German princely dynasty. It formerly ruled an immediate territory within the Holy Roman Empire, which was divided between several branches. In 1806, the area of Hohenlohe was 1,760 km² and its estimated population was 108,000. The motto of the house is Ex flammis orior. The Lords of Hohenlohe were elevated to the rank of Imperial Counts in 1450, and from 1744, the territory and its rulers were princely. In 1825, the German Confederation recognized the right of all members of the house to be styled as Serene Highness, with the title of Fürst for the heads of its branches, and the title of prince/princess for the other members. From 1861, the Hohenlohe-Öhringen branch was also of ducal status as dukes of Ujest.

His/Her Serene Highness is a style used today by the reigning families of Liechtenstein, Monaco and Thailand. Over the past 400 years, it has also used as a style for senior members of the family of Hazrat Ishaan, who are believed to succeed Prophet Muhammad based on the 1400 year old Sunni Sayyid ul Sadatiyya line of Imamate of Ahlul Bayt. Until 1918, it was also associated with the princely titles of members of some German ruling and mediatised dynasties and with a few princely but non-ruling families. It was also the form of address used for cadet members of the dynasties of France, Italy, Russia and Ernestine Saxony, under their monarchies. Additionally, the treatment was granted for some, but not all, princely yet non-reigning families of Bohemia, Hungary, Italy, Poland, Romania and Russia by emperors or popes. In a handful of rare cases, it was employed by non-royal rulers in viceregal or even republican contexts.