Human extinction is the hypothetical end of the human species, either by population decline due to extraneous natural causes, such as an asteroid impact or large-scale volcanism, or via anthropogenic destruction (self-extinction), for example by sub-replacement fertility.

Extinction is the termination of a taxon by the death of its last member. A taxon may become functionally extinct before the death of its last member if it loses the capacity to reproduce and recover. Because a species' potential range may be very large, determining this moment is difficult, and is usually done retrospectively. This difficulty leads to phenomena such as Lazarus taxa, where a species presumed extinct abruptly "reappears" after a period of apparent absence.