Interstate 190 is a north–south auxiliary Interstate Highway in the United States that connects I-90 in Buffalo, New York, with the Canada–United States border at Lewiston, New York, near Niagara Falls. Officially, I-190 from I-90 north to New York State Route 384 (NY 384) is named the Niagara Thruway and is part of the New York State Thruway system. The remainder, from NY 384 to Lewiston, is known as the Niagara Expressway and is maintained by the New York State Department of Transportation (NYSDOT).

Interstate 90 (I-90) is a part of the Interstate Highway System that runs from Seattle, Washington, to Boston, Massachusetts. In the US state of New York, I-90 extends 385.48 miles (620.37 km) from the Pennsylvania state line at Ripley to the Massachusetts state line at Canaan, and is the second-longest highway in the state after New York State Route 17 (NY 17). Although most of the route is part of the tolled New York State Thruway, two non-tolled sections exist along I-90. Within New York, I-90 has a complete set of auxiliary Interstates, which means that there are Interstates numbered I-190 through I-990 in the state, with no gaps in between. For most of its length in New York, I-90 runs parallel to the former Erie Canal route, NY 5, US Route 20 (US 20) and the CSX Transportation railroad mainline that traverses the state.