Interstate 69 (I-69) is a proposed Interstate Highway that will pass through the western part of the US state of Tennessee, serving the cities of Union City, Dyersburg, and Memphis. Currently, a 21-mile (34 km) section of already-existing freeway in Memphis has been approved for the I-69 designation while another segment near Union City opened on February 21, 2024, under the temporary designation of Tennessee State Route 690. However, state officials have stated that they will not commit to finishing the interstate in their state until they receive more federal funding.

U.S. Route 51 (US 51), mostly overlapped by the unsigned State Route 3 (SR 3), is a north–south state highway in the U.S. state of Tennessee, that is 135.9 miles (218.71 km) long, completely within West Tennessee. It begins in Shelby County and ends in Obion County. The SR 3 designation is seen largely on mileposts.