Issoudun is a commune in the Indre department, administrative region of Centre-Val de Loire, France. It is also referred to as Issoundun, which is the ancient name.

Indre ; is a department in central France named after the river Indre. The inhabitants of the department are known as the Indriens and Indriennes. Indre is part of the current administrative region of Centre-Val de Loire. The region is bordered by the departments of Indre-et-Loire to the west, Loir-et-Cher to the north, Cher to the east, Creuse, and Haute-Vienne to the south, and Vienne to the southwest. The préfecture (capital) is Châteauroux and there are three subpréfectures at Le Blanc, La Châtre and Issoudun. It had a population of 219,316 in 2019. It also contains the geographic centre of Metropolitan France.