The Italian Grand Prix is the fifth oldest national motor racing Grand Prix, having been held since 1921. Since 2013, it has been the Grand Prix held the most times, with 93 editions as of 2023. It is one of the two Grands Prix which has run as an event of the Formula One World Championship Grands Prix every season, continuously since the championship was introduced in 1950. Every Formula One Italian Grand Prix in the World Championship era has been held at Monza except in 1980, when it was held at Imola.

Grand Prix motor racing, a form of motorsport competition, has its roots in organised automobile racing that began in France as early as 1894. It quickly evolved from simple road races from one town to the next, to endurance tests for car and driver. Innovation and the drive of competition soon saw speeds exceeding 100 miles per hour (160 km/h), but because early races took place on open roads, accidents occurred frequently, resulting in deaths both of drivers and of spectators. A common abbreviation used for Grand Prix racing is "GP" or "GP racing".