John Komnenos Asen was the ruler of the Principality of Valona from c. 1345 to 1363, initially as a vassal of the Serbian Empire, and after 1355 as a largely independent lord. Descended from high-ranking Bulgarian nobility, John was a brother of both Tsar Ivan Alexander of Bulgaria and Helena of Bulgaria, the wife of Tsar Stephen Dušan of Serbia. Perhaps in search of better opportunities, he emigrated to Serbia, where his sister was married. There, he was granted the title of despot by Stephen Dušan, who placed him in charge of his territories in modern south Albania.

Helena of Bulgaria was a Bulgarian princess, and the Queen and Empress consort of Serbia by marriage to Serbian King and later Emperor Stefan Dušan. She was a regent of Serbia between 1355 and 1356 for her son Stefan Uroš V.