Lives of the Mayfair Witches is a trilogy of supernatural horror/fantasy novels by American novelist Anne Rice. It centers on a family of witches whose fortunes have been guided for generations by a spirit named Lasher. The series began in 1990 with The Witching Hour, which was followed by the sequels Lasher (1993) and Taltos (1994). All three novels debuted at No. 2 on The New York Times Best Seller list.

Anne Rice was an American author of gothic fiction, erotic literature, and bible fiction. She is best known for writing The Vampire Chronicles. Rice later adapted the first novel of the series into a commercially successful eponymous film, Interview with the Vampire (1994).