Enoch Lloyd Branson (1853–1925) was an American artist best known for his portraits of Southern politicians and depictions of early East Tennessee history. One of the most influential figures in Knoxville's early art circles, Branson received training at the National Academy of Design in the 1870s and subsequently toured the great art centers of Europe. After returning to Knoxville, he operated a portrait shop with photographer Frank McCrary. He was a mentor to fellow Knoxville artist Catherine Wiley, and is credited with discovering twentieth-century modernist Beauford Delaney.

Anna Catherine Wiley was an American artist active primarily in the early twentieth century. After training with the Art Students League of New York and receiving instruction from artists such as Lloyd Branson and Frank DuMond, Wiley painted a series of impressionist works that won numerous awards at expositions across the Southern United States, and have since been displayed in museums such as the Metropolitan Museum of Art and the Morris Museum of Art. In 1926, Wiley was institutionalized after suffering a mental breakdown, and never painted again.