The M53 is an 18.9-mile (30.4 km) motorway in the Metropolitan Borough of Wirral, Merseyside and the borough of Cheshire West and Chester, Cheshire on the Wirral Peninsula in England. It is also referred to as the Mid Wirral Motorway. It runs between the Kingsway Tunnel, at Wallasey in the north, and the A55 at Chester.

Merseyside is a ceremonial and metropolitan county in North West England. It borders Lancashire to the north, Greater Manchester to the east, Cheshire to the south, the Welsh county of Flintshire across the Dee Estuary to the southwest, and the Irish Sea to the west. The largest settlement is the city of Liverpool.