Manila, officially the City of Manila, is the capital and second-most-populous city of the Philippines. Located on the eastern shore of Manila Bay on the island of Luzon, it is classified as a highly urbanized city. As of 2019, it is the world's most densely populated city proper. It was the first chartered city in the country, and was designated as such by the Philippine Commission Act No. 183 on July 31, 1901. It became autonomous with the passage of Republic Act No. 409, "The Revised Charter of the City of Manila", on June 18, 1949. Manila is considered to be part of the world's original set of global cities because its commercial networks were the first to extend across the Pacific Ocean and connect Asia with the Spanish Americas through the galleon trade; when this was accomplished, it was the first time an uninterrupted chain of trade routes circling the planet had been established.

The Manila galleon, originally known as La Nao de China, and Galeón de Acapulco, refers to the Spanish trading ships that linked the Spanish Crown's Viceroyalty of New Spain, based in Mexico City, with its Asian territories, collectively known as the Spanish East Indies, across the Pacific Ocean. The ships made one or two round-trip voyages per year between the ports of Acapulco and Manila from the late 16th to early 19th century. The name of the galleon changed to reflect from which city the ship sailed, setting sail from Cavite, in Manila Bay, at the end of June or first week of July, starting the return journey (tornaviaje) from Acapulco in March–April of the next calendar year, and returning to Manila in June–July.