Manningtree railway station is on the Great Eastern Main Line (GEML) in the East of England, serving the town of Manningtree, Essex. It is 59 miles 35 chains (95.66 km) down the line from London Liverpool Street and is situated between Colchester to the west and Ipswich to the east. The three-letter station code is MNG. It is also the western terminus of the Mayflower Line, a branch line to Harwich Town. The following station on the branch is Mistley.

The Great Eastern Main Line is a 114.5-mile (184.3 km) major railway line on the British railway system which connects Liverpool Street station in central London with destinations in east London and the East of England, including Shenfield, Chelmsford, Colchester, Ipswich and Norwich. Its numerous branches also connect the main line to Southminster, Braintree, Sudbury, Harwich and a number of coastal towns including Southend-on-Sea, Clacton-on-Sea, Walton-on-the-Naze and Lowestoft.