Margot Betti Frank was the elder daughter of Otto Frank and Edith Frank and the elder sister of Anne Frank. Margot's deportation order from the Gestapo hastened the Frank family into hiding. According to the diary of her younger sister, Anne, Margot kept a diary of her own, but no trace of it has ever been found. She died in Bergen-Belsen concentration camp from a typhus outbreak.

Otto Heinrich Frank was the father of Anne Frank. He edited and published the first edition of her diary in 1947 and advised on its later theatrical and cinematic adaptations. In the 1950s and 60s he established European charities in his daughter's name and founded the trust which preserved his family's wartime hiding place, the Anne Frank House, in Amsterdam.