Marion Sims Wyeth was an American architect known for his range in styles such as Art Deco, Mediterranean Revival, and classical Georgian, French, and Colonial. He designed numerous mansions in Palm Beach, Florida during its gilded age. Wyeth was among a group of architects considered the “Big Five,” along with John L. Volk, Addison Mizner, Maurice Fatio, and Howard Major, who defined Palm Beach style in the early twentieth century.

James Marion Sims was an American physician in the field of surgery. His most famous work was the development of a surgical technique for the repair of vesicovaginal fistula, a severe complication of obstructed childbirth. He is also remembered for inventing the Sims speculum, Sims sigmoid catheter, and the Sims position. Against significant opposition, he established, in New York, the first hospital specifically for women. He was forced out of the hospital he founded because he insisted on treating cancer patients; he played a small role in the creation of the nation's first cancer hospital, which opened after his death.