Mendoza, officially Province of Mendoza, is a province of Argentina, in the western central part of the country in the Cuyo region. It borders San Juan to the north, La Pampa and Neuquén to the south, San Luis to the east, and the republic of Chile to the west; the international limit is marked by the Andes mountain range. Its capital city is the homonymous city of Mendoza.

Cuyo is the wine-producing, mountainous region of central-west Argentina. Historically it comprised the provinces of San Juan, San Luis and Mendoza. The modern New Cuyo includes both Cuyo proper and the province of La Rioja. New Cuyo is a political and economic macroregion, but culturally La Rioja is part of the North-West rather than of Cuyo.