Midtown Detroit is a commercial and residential district located along the east and west side of Woodward Avenue, north of Downtown Detroit, and south of the New Center area. The area includes several historic districts. In addition, it contains a residential area of some 14,550 people and covers 2.09 sq mi. The community area of neighborhoods is bounded by the Chrysler Freeway (I-75) on the east, the Lodge Freeway (M-10) on the west, the Edsel Ford Freeway (I-94) on the north, and the Fisher Freeway (I-75) on the south.

M-1, also known as Woodward Avenue, is a north–south state trunkline highway in the Metro Detroit area of the US state of Michigan. The highway, called "Detroit's Main Street", runs from Detroit north-northwesterly to Pontiac. It is one of the five principal avenues of Detroit, along with Michigan, Grand River, Gratiot, and Jefferson avenues. These streets were platted in 1805 by Judge Augustus B. Woodward, namesake to Woodward Avenue. The Federal Highway Administration (FHWA) has listed the highway as the Automotive Heritage Trail, an All-American Road in the National Scenic Byways Program. It has also been designated a Pure Michigan Byway by the Michigan Department of Transportation (MDOT), and was also included in the MotorCities National Heritage Area designated by the US Congress in 1998.