Miguel Mateo Maldonado y Cabrera (1695–1768) was a Mestizo painter born in Oaxaca but moved to Mexico City, the capital of Viceroyalty of New Spain. During his lifetime, he was recognized as the greatest painter in all of New Spain. He created religious and secular art for the Catholic Church and wealthy patrons. His casta paintings, depicting interracial marriage among Amerindians, Spaniards and Africans, are considered among the genre's finest. Cabrera's paintings range from tiny works on copper to enormous canvases and wall paintings. He also designed altarpieces and funerary monuments.

Mestizo is a person of mixed European and Indigenous non-European ancestry in the former Spanish Empire. In certain regions such as Latin America, it may also refer to people who are culturally European even though their ancestors are Indigenous. The term was used as an ethno-racial exonym for mixed-race castas that evolved during the Spanish Empire. It was a formal label for individuals in official documents, such as censuses, parish registers, Inquisition trials, and others. Priests and royal officials might have classified persons as mestizos, but individuals also used the term in self-identification.