The Monroe Doctrine is a United States foreign policy position that opposes European colonialism in the Western Hemisphere. It holds that any intervention in the political affairs of the Americas by foreign powers is a potentially hostile act against the United States. The doctrine was central to American grand strategy in the 20th century.

The officially stated goals of the foreign policy of the United States of America, including all the bureaus and offices in the United States Department of State, as mentioned in the Foreign Policy Agenda of the Department of State, are "to build and sustain a more democratic, secure, and prosperous world for the benefit of the American people and the international community". Liberalism has been a key component of US foreign policy since its independence from Britain. Since the end of World War II, the United States has had a grand strategy which has been characterized as being oriented around primacy, "deep engagement", and/or liberal hegemony. This strategy entails that the United States maintains military predominance; builds and maintains an extensive network of allies ; integrates other states into US-designed international institutions ; and limits the spread of nuclear weapons.