Mount Holyoke College is a private liberal arts women's college in South Hadley, Massachusetts, United States. It is the oldest member of the historic Seven Sisters colleges, a group of historically female colleges in the Northeastern United States. The college was founded in 1837 as the Mount Holyoke Female Seminary by Mary Lyon, a pioneer in education for women. Mount Holyoke is part of the Five College Consortium in Western Massachusetts.

Women's colleges in the United States are private single-sex U.S. institutions of higher education that only admit female students. They are often liberal arts colleges. There are approximately 26 active women's colleges in the United States in 2024, down from a peak of 281 such colleges in the 1960s.