New York State Route 75 (NY 75) is a north–south state highway in Erie County, New York, in the United States. It extends for 20.85 miles (33.55 km) from an intersection with NY 39 in the Collins hamlet of Collins Center to an interchange with NY 5 in the town of Hamburg. The route passes through the village of Hamburg, which serves as the northern terminus of a 2-mile (3.2 km) overlap between U.S. Route 62 (US 62) and NY 75. Past Hamburg, NY 75 connects to the New York State Thruway northwest of the village before ending a short distance from Lake Erie. The portion of NY 75 south of Hamburg is a two-lane rural highway; in contrast, the section north of the village is four lanes wide and serves commercial and residential areas.

New York State Route 39 (NY 39) is an east–west state highway in the western portion of New York in the United States. It begins and ends at intersections with U.S. Route 20 (US 20) 98.89 miles (159.15 km) apart. The western terminus of NY 39 is east of Fredonia in the Chautauqua County town of Sheridan, while the eastern terminus is in the Livingston County village of Avon. At its east end, NY 39 also ends at NY 5, which is concurrent to US 20 at this point. NY 39 serves several villages, including Gowanda and Geneseo, and intersects a handful of major north–south highways, such as US 219 in Springville and NY 19 near Pike. Most of the route is a two-lane highway that passes through rural, undeveloped areas.