Newberry County is a county located in the U.S. state of South Carolina. As of the 2020 census, its population was 37,719. Its county seat is Newberry. The name is of unknown origin, although one theory suggests that it was named by Quaker settlers in honor of their home of Newberry, a suburb of London in the United Kingdom.

South Carolina's 3rd congressional district is a congressional district in western South Carolina bordering both Georgia and North Carolina. It includes all of Abbeville, Anderson, Edgefield, Greenwood, Laurens, McCormick, Oconee, Pickens, and Saluda counties and portions of Greenville and Newberry counties. The district is mostly rural, but much of the economy revolves around the manufacturing centers of Anderson and Greenwood. With a Cook Partisan Voting Index rating of R+21, it is the most Republican district in South Carolina.