Nuuk is the capital of and most populous city in Greenland, an autonomous territory in the Kingdom of Denmark. Nuuk is the seat of government and the territory's largest cultural and economic center. The major cities from other countries closest to the capital are Iqaluit and St. John's in Canada and Reykjavík in Iceland. Nuuk contains a third of Greenland's population and its tallest building. Nuuk is also the seat of government for the Sermersooq municipality. In January 2023, it had a population of 19,604. Nuuk is considered a modernized city after the policy began in 1950.

Greenland is a North American autonomous territory of the Kingdom of Denmark. It is the larger of two autonomous territories within the Kingdom, the other being the Faroe Islands; the citizens of both territories are full citizens of Denmark. As Greenland is one of the Overseas Countries and Territories of the European Union, citizens of Greenland are European Union citizens. The capital and largest city of Greenland is Nuuk. Greenland lies between the Arctic and Atlantic oceans, east of the Canadian Arctic Archipelago. It is the world's largest island, and is the location of the northernmost area of the world – Kaffeklubben Island off the northern coast is the world's northernmost undisputed point of land, and Cape Morris Jesup on the mainland was thought to be so until the 1960s.