King's Highway 10, commonly referred to as Highway 10, is a provincially maintained highway in the Canadian province of Ontario. The highway connects the northern end of Highway 410 just north of Brampton with Owen Sound on the southern shores of Georgian Bay, passing through the towns of Orangeville and Shelburne as well as several smaller villages along the way. It historically followed the Toronto–Sydenham Road, the southern part of which later became the southern section of Hurontario Street. The section between Orangeville and Primrose was formerly part of Prince of Wales Road, which continues northwards after the highway turns west. Between Chatsworth and Owen Sound, Highway 10 is concurrent with Highway 6.

The Provincial Highway Network consists of all the roads in Ontario maintained by the Ministry of Transportation of Ontario (MTO), including those designated as part of the King's Highway, secondary highways, and tertiary roads. Components of the system—comprising 16,900 kilometres (10,500 mi) of roads and 2,880 bridges —range in scale from Highway 401, the busiest highway in North America, to unpaved forestry and mining access roads. The longest highway is nearly 2,000 kilometres (1,200 mi) long, while the shortest is less than a kilometre. Some roads are unsigned highways, lacking signage to indicate their maintenance by the MTO; these may be remnants of highways that are still under provincial control whose designations were decommissioned, roadway segments left over from realignment projects, or proposed highway corridors.